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Immune System Dysfunction in the Elderly Anais da ABC (AABC)
FUENTES,EDUARDO; FUENTES,MANUEL; ALARCÓN,MARCELO; PALOMO,IVÁN.
ABSTRACT Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity established as immunosenescence. Immunosenescence is a new concept that reflects the age-associated restructuring changes of innate and adaptive immune functions. Thus elderly individuals usually present chronic low-level inflammation, higher infection rates and chronic diseases. A study of alterations in the immune system during aging could provide a potentially useful biomarker for the evaluation of immune senescence treatment. The immune system is the result of the interplay between innate and adaptive immunity, yet the impact of aging on this...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Aging; Immunosenescence; Adaptive immunity; Innate immunity; Inflammation..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100285
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Mechanisms of Endothelial Protection by Natural Bioactive Compounds from Fruit and Vegetables Anais da ABC (AABC)
MONSALVE,BERNARDITA; CONCHA-MEYER,ANIBAL; PALOMO,IVÁN; FUENTES,EDUARDO.
ABSTRACT The endothelium is fundamental for the regulation of vascular tone and structure. Under disease conditions, including the presence of cardiovascular disease risk factors, the endothelium loses its protective role and becomes a proatherosclerotic structure. In this article we searched for strategies from PUBMED and Science Direct databases using the following key words: endothelium, natural bioactive compounds, polyphenols and cardiovascular diseases. The search was restricted to english language papers. Studies have identified the contribution of diet to the risk of developing cardiovascular diseases. In this context, high intakes of fruit and vegetables are associated with the decrease of cardiovascular diseases. Thus the most important...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Endothelium; Natural bioactive compounds; Polyphenols; Cardiovascular diseases.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200615
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